NHS-12-Biotin

NHS-12-Biotin

Catalog	BR00028455
Description	NHS-12-Biotin is a derivative of D-biotin, a amine-reactive biotinylation agent, that contains a spacer arm off the valeric acid side chain of D-biotin with an NHS ester group at its end. The NHS ester group at the end of NHS-12-Biotin covalently binds to amine groups in proteins and other molecules forming a stable amide linkage and releasing the NHS group. NHS-12-Biotin has a greater length between a covalently modified molecule and the bicyclic biotin rings than NHS-LC-Biotin, which provides the avidin or streptavidin probes a greater opportunity to reach the binding sites deeply buried inside the surface plane of proteins. NHS-12-Biotin is insoluble in aqueous environments requiring the dissolution of organic solvents prior to the addition to a buffered reaction.
IUPAC Name	2,5-dioxopyrrolidin-1-yl 4-(6-(5-((3aS,4S,6aR)-2-oxohexahydro-1H-thieno[3,4-d]imidazol-4-yl)pentanamido)hexanamido)butanoate
Molecular Weight	539.64 g/mol
Molecular Formula	C24H37N5O7S
Canonical SMILES	O=C1N[C@@]([H])([C@]([H])(CS2)N1)[C@@H]2CCCCC(NCCCCCC(NCCCC(ON3C(CCC3=O)=O)=O)=O)=O
Purity	0.98
Storage	Store at -20°C
Shipping	Small Molecules with Blue Ice, Modified Nucleotides with Dry Ice.

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