Protein Biotinylation and Targeted Drug Delivery

At present, more and more studies combine protein biotinylation and drug delivery to achieve efficient drug immobilization and drug release. Intravascular protein biotinylation can be used to coat biotinylated drugs to achieve rapid and efficient drug delivery. The design of drug delivery based on protein biotinylation will be in the development stage for a long time, with huge potential and development space. Alfa Chemistry researchers have long been committed to the research of protein biotinylation and can provide related services. Based on the current research and exploration, the services we can provide about protein biotinylation for targeted drug delivery include intravascular drug delivery, targeted drug delivery and ovarian cancer drug delivery. In the future, we will combine protein biotinylation and intelligent materials, and develop more methods and strategies for efficient drug delivery and more precise drug release.

The Services

Alfa Chemistry has a sound service system and fast-response project management, focusing on high-quality service and support to meet customer needs. We provide high-quality protein biotinylation services for global customers, and are committed to designing efficient drug delivery systems and striving to expand them to meet wider application needs. The related services we can provide include but are not limited to:

• Protein biotinylation for intravascular drug delivery

Endothelial cells (ECs) are involved in important physiological activities, including angiogenesis in atherosclerosis and cancer, and controlling ECs can greatly facilitate the treatment of diseases. Combining protein biotinylation and drug therapy to deliver drugs into blood vessels can achieve efficient drug immobilization.

• Site-targeted drug delivery of biotinylated proteins

Protein biotinylation is used in the field of efficient drug delivery. Based on the strong affinity, the targeted delivery of high-efficiency drugs can be realized, which is of great significance for the research of new drugs.

• Streptavidin fusion proteins and drug delivery in ovarian cancer

Ovarian cancer is one of the most common malignant tumors affecting women's health, with a high mortality rate. Biotinylation-based therapeutic or inhibitory materials may be an alternative approach to provide multiple highly effective treatments for ovarian cancer.

Our service advantages

• Professional protein biotinylation platform, suitable for efficient drug delivery
• Efficient and professional data analysis, supporting intelligent data comparison
• Rapid correlation reaction protein biotinylation project
• Extensive protein biotinylation strategies

Protein biotinylation platform for drug delivery

In recent years, biotin-avidin/streptavidin has been widely used in the fields of affinity purification, medical detection, drug delivery and release, etc. A special platform for protein biotinylation for drug delivery, with the following characteristics:

• Site-specific controllable biotinylation and drug delivery
• Various biotin-avidin/streptavidin system options
• Experimental variation between batches is small
• Biotinylated proteins are subject to rigorous activity assays
• Rich database covering all hot drug targets
• Wide application

Figure 2. A specialized platform that provides efficient protein biotinylation services for efficient drug delivery

Prospects

The biotin-avidin system can be widely used in many fields in the field of biomedicine, such as affinity purification and directional delivery of drugs. In order to ensure the targeting and effective aggregation of therapeutic drug molecules, a biotin-avidin transport system coupled with drugs has been developed. Improve the functional properties of avidin to promote the development of intelligent and efficient systems, research and application in affinity purification, medical signal detection, drug delivery, vaccine development and tissue engineering, etc.

What can we provide?

• Support global customer payments
• Professional Data Analysis
• Fast Project Response
• Professional protein biotinylation platform
• Precise solution

Alfa Chemistry provides efficient protein biotinylation services for efficient drug delivery. If you are interested in our services, please contact us immediately.

References:

1. Kayla. N. B.; et al. Protein biotinylation and targeted drug delivery for affinity purification and identification of RNA-protein interactions. ACS Chem. Biol. 2020, 15(8): 2247-2258.
2. Tsuneaki. A.; et al. A human biotin acceptor domain allows site-specific conjugation of an enzyme to an antibody-avidin fusion protein for targeted drug delivery. Biomolecular Engineering. 2005, 21(6): 145-155.

※ It should be noted that our service is only used for research, not for clinical use.

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