Avidin-biotin System Service

Avidin is a protein found in birds and amphibians that has a high affinity for biotin. Biotin is a cofactor that functions in multikaryotic eukaryotic processes. The interaction between avidin and biotin is the strongest known and is ideal for purification and detection strategies. The avidin-biotin system is a typical biological reaction amplification system widely used in biochemical analysis, medical diagnosis, localization monitoring, affinity purification and drug delivery. The avidin-biotin system can be combined with a variety of labels, making biological detection more sensitive. Based on the robust interaction between biotin and avidin, a variety of detection systems have been derived for broader applications. The avidin-biotin system has shown great advantages in practical applications, mainly high sensitivity, high specificity, high stability and wide applicability. Alfa Chemistry supports the expansion of the application of avidin-biotin system in the biological field, and also supports customized services, insisting on meeting customers' needs with high-quality services.

The Services

Biotin-avidin system is widely used in biological diagnosis, drug delivery and biological analysis, and is an important tool for biological research. Alfa Chemistry researchers have a professional team with many years of experience in related fields, a professional quality control platform, and can provide complete biotin-avidin services, including but not limited to:

• Avidin-biotin system for delivery of biomolecules

The avidin-biotin system is used in nano-delivery systems for drugs, including small molecule drugs, small bioassays, antibodies, proteins, vaccines, monoclonal antibodies and nucleic acids.

• Pretargeting strategy using avidin-biotin system

The multifunctionality of pretargeting offers great application potential for tumor diagnosis and therapy, but its development still faces great challenges.

• Avidin-biotin for delivery of diagnostic reagents

Biotin and avidin have strong affinity, and the system has good binding stability and high specificity. The avidin-biotin system can construct a multi-stage signal amplification system, which can be widely used in the fields of immunohistochemistry, enzyme-linked immunosorbent assay, biological diagnosis, gene probe and molecular biology.

• Avidin-biotin complexes for bioanalytical applications

The powerful biotin-avidin complex system serves as an effective research tool in the field of biological research, including biodiagnostics and gene therapy. Alfa Chemistry strives to expand the application in the field of biomolecules, including: affinity chromatography, immunodiagnosis, gene probes and localization observation.

Quality control and quality assurance

• Quality assurance system: Alfa Chemistry has first-class quality control practices and always adheres to industry norms. The biotin-avidin complexes we provide need to undergo rigorous qualitative or quantitative analysis.
• Advanced instruments: We have the world's most advanced equipment and instruments to ensure the reliability of the compound. A high level of quality and compliance is provided during the customization process, and our service quality is trustworthy.
• Product certification: Related solutions will ensure the feasibility of the manufacturing process, and each series of biotin-avidin complexes will undergo rigorous testing and match professional certificates.
• Quality inspection center: With leading instruments, it supports the testing of various equipment, such as nuclear magnetic (NMR), X-ray diffraction (XRD), infrared (IR), melting point detection, refractive index detection, various electrophoresis, particle size detection, comparison Optical rotation detection and density detection, etc. Quantification includes nuclear magnetic resonance (NMR), liquid chromatography (HPLC), gas chromatography (GC), mass spectrometry (MS), electrophoresis, fluorescence spectroscopy (XRF), fluorescence quantification and various titrations, etc.

Figure 2. We have the ability to provide customers with quality services to meet their needs

Technical team and support

Our analytical chemists, molecular biologists and research teams give our services an edge and support our clients' custom development needs. We invest in advanced equipment and support analysis with high-tech means to ensure data reliability. We have the capability to provide high quality biotin-avidin systems, and continuous analysis promotes a comprehensive understanding of customers.

Alfa Chemistry can strictly control the quality of service and insist on meeting the needs of customers with high-quality services. If you are interested in our services, please contact us immediately.

References:

1. Antonio. S.; et al. Fast track selection of immunogens for novel vaccines through visualisation of the early onset of the B-cell response. Vaccine. 2005, 23: 1900-1909.
2. Paganelli. G.; et al. Pretargeting of carcinomas with the avidin-biotin system. Int J Biol Markers. 1993, 8(3):155-159.

※ It should be noted that our service is only used for research, not for clinical use.