Protein Biotinylation Immobilization

Protein participates in important biological activities, can constitute important hormones and various enzymes, can participate in heredity, maintain osmotic pressure and regulate immune function. In recent years, with the development of biotechnology, protein immobilization technology has also developed rapidly. Protein immobilization can be carried out by means of adsorption immobilization and covalent linkage of chemical bonds. Efficient immobilization of proteins can enhance their stability in complex environments, and is a common way to improve the value of proteins. Biotinylation is the process of combining biotin and other biomolecules, which can be widely used in efficient protein purification, separation and detection. Many currently known proteins can be modified by biotinylation groups, so as to achieve the purpose of efficient immobilization of proteins. Developing an efficient and green protein biotinylation immobilization method is currently a difficult problem. Alfa Chemistry has a professional research team, which has long been committed to the research of protein biotinylation and immobilization, and provides customers with satisfactory services.

The Services

Alfa Chemistry focuses on efficient protein biotinylation services and insists on meeting customers' needs with professional services. The efficient protein biotinylation immobilization services we can provide include but are not limited to:

• Phospholipid biotinylation for protein immobilization

Protein immobilization technology has received extensive attention in recent years and has also made great progress. The composition of protein is complex, and the spatial structure is diverse and flexible, which brings great challenges to the process of protein immobilization.

• Site-specific immobilization of protein biotinylation

The study of site-specific immobilization of protein biotinylation can facilitate the development of large-scale assays to reveal the biological functions of proteins.

• Synthesis of protein biotinylation immobilization matrix

Efficient immobilization of proteins is critical to biotechnology and plays an important role in analytical and biomedical fields.

Our service advantage

• We support efficient protein biotinylation and immobilization services and provide professional data analysis
• Professional quality control platform, strictly control service quality and efficiency
• Extensive customer support, serving scientific research institutions and teams around the world
• Project responsive protein immobilization biotinylation services
• Professional research team to support efficient biotinylation services

Figure2. Optimized service system, professional biotinylation strategy to meet customer needs

Methods of protein immobilization

Protein is an important biological macromolecule, which plays an important role in the regulation of metabolic process of organisms, biological heredity, biological cycle control and information exchange. The choice of protein immobilization method depends on factors such as immobilization surface properties, protein characteristics and immunoassay methods. Protein immobilization methods can be divided into:

• Adsorption immobilization
• Covalent linkage of chemical bonds

Alfa Chemistry provides efficient protein biotinylation immobilization services, provides a wide range of biotinylation strategies, and insists on meeting customer needs. If you are interested in our services, please contact us immediately.

References:

1. Huang. B.; et al. Phospholipidbiotinylation of polydimethylsiloxane (PDMS) for protein immobilization. Lab Chip, 2006, 6: 369-373.
2. Rina Y. P. L.; et al. Site-specific immobilization of biotinylated proteins for protein microarray analysis. Methods in Molecular Biology. 2012, 246: 85-100.
3. Danielle M. W.; et al. Facile protein immobilization using engineered surface-active biofilm proteins. ACS Appl. Nano Mater. 2018, 1：2483-2488.

※ It should be noted that our service is only used for research, not for clinical use.