Biotin and Targeted Drug Delivery

Biotin has the characteristics of simple structure, few functional groups and small steric hindrance, and participates in the metabolism of carbohydrates, lipids and amino acids in cells. Biotin receptors are overexpressed in cancer cells and can be used as markers of cancer cells. Biotin is easy to be modified to form derivatives with various active groups, which can be widely used in the fields of biological diagnosis and disease treatment. The biotin-modified drug carrier can enhance the targeting of the drug, help to improve the therapeutic effect and reduce the toxicity of the drug. Targeted drug delivery enhances drug accumulation at the tumor site to reduce exposure to normal healthy tissue. The development of tumor-specific drug delivery systems that recognize both normal and tumor cells is an urgent need for effective cancer treatment. Alfa Chemistry has a professional biotechnology team that can support the development and preparation of high-quality materials and strive to expand their applications in the field of targeted drug delivery.

The Services

Alfa Chemistry can provide customers with professional targeted drug delivery research, drug release and control, and is committed to providing customers with professional services. Our related services include but are not limited to:

• Construction of biotin targeted drug delivery system

Biotin receptors are overexpressed in cancer cells, and biotin can be used as a targeting ligand to increase tumor-specific cellular uptake, so biotin receptors can be used as markers of cancer cells. Biotin-modified drug carriers can enhance targeting, aiming to improve therapeutic efficacy and reduce drug toxicity.

• Preparation of biotin materials for targeted drug delivery

The effectiveness of cancer therapy largely depends on the efficiency of tumor-specific drug delivery. The development of tumor-specific drug delivery systems that recognize both normal and tumor cells is an urgent need for effective cancer treatment.

Our team support and strength

• R & D team: With rich experience, equipped with advanced equipment, can provide efficient related services
• Cooperative team: Established a good cooperative relationship with the world's leading team to meet a wide range of needs

Advantages and features of biotin-based drug delivery systems

• Support a more reasonable strategy to realize the gradual upgrade of the system
• Scalable biotin-based targeted drug delivery platform
• Versatile biotin-targeted

What can we provide?

Alfa Chemistry focuses on the analysis and experiments of biotinylated samples, and provides efficient biotinylation solutions for global customers to meet biotinylation-related needs. The services we provide have the following advantages:

Alfa Chemistry's scientific researchers have been engaged in related fields for many years and have many years of experience. At the same time, they are equipped with advanced laboratories, which can carry out customized solution design, material characterization and sample testing according to customer needs. In addition, we also have a professional quality control system, which can effectively control the quality. The professional support including:

• Build a professional targeted drug delivery system
• professional solution
• Can be used for the preparation and detection of biotin-modified nanomaterials
• Development of various systems

Alfa Chemistry has a professional biotechnology team that can provide customers with high-quality professional targeted drug delivery services. If you are interested in our services, please contact us immediately.

References:

1. Welson. W. S.; et al. Design of a bifunctional fusion protein for ovarian cancer drug delivery: Single-chain anti-CA125 core-streptavidin fusion protein. European Journal of Pharmaceutics and Biopharmaceutics. 2007,65(3): 398-405.
2. Nazanin. R.; et al. Recent trends in targeted therapy of cancer using graphene oxide-modified multifunctional nanomedicines. Journal of Drug Targeting. 2016, 25(4): 202-215.

※ It should be noted that our service is only used for research, not for clinical use.

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