Desthiobiotin-PEG4-Alkyne

Desthiobiotin-PEG4-Alkyne

Catalog	BR00028800
CAS	1802907-99-8
Structure
Description	Desthiobiotin is a single-ring, sulfur-free analog of biotin that binds to streptavidin with nearly equal specificity but less affinity than biotin (Kd = 1011 vs. 1015M, respectively). Consequently, desthiobiotinylated proteins can be eluted readily and specifically from streptavidin affinity resin using mild conditions based on competitive displacement with free biotin. For pull-down experiments with biological samples, this soft-release characteristic of desthiobiotin also helps to minimize co-purification of endogenous biotinylated molecules, which remain bound to streptavidin upon elution of the target protein complexes with free biotin. Reagent grade, for research purpose. Please contact us for GMP-grade inquiries.
Molecular Weight	427.5 g/mol
Molecular Formula	C21H37N3O6
Purity	90%
Storage	-20°C
Shipping	Ambient Temperature

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