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Catalog | BR00028483 |
CAS | 325143-98-4 |
Structure | ![]() |
Description | Sulfo-NHS-SS-biotin(sulfosuccinimidyl-20(biotinamido)ethyl-1,3-dithiopropionate) is a long-chain cleavable amine-reactive biotinylation reagent. The presence of the negatively charged sulfonate group in the chemical structure of sulfo-NHS-SS-biotin makes it a water-soluble biotinylation reagent that can be directly added to aqueous reactions without prior dissolution of organic solvents. Although no prior dissolution is required, an aqueous stock solution of sulfo-NHS-SS-biotin must be prepared rapidly and used immediately in case of the occurrence of hydrolysis of the active ester. Sulfo-NHS-SS-biotin has been used to react with amine-containing proteins and other molecules forming a complex which further interacts with avidin or streptavidin probes and to purify targeted molecules using affinity chromatography on a column of immobilized avidin or streptavidin. |
Synonyms | Biotin disulfide N-hydroxysulfosuccinimide ester |
IUPAC Name | sodium;1-[3-[2-[5-[(3aS,4S,6aR)-2-oxo-1,3,3a,4,6,6a-hexahydrothieno[3,4-d]imidazol-4-yl]pentanoylamino]ethyldisulfanyl]propanoyloxy]-2,5-dioxopyrrolidine-3-sulfonate |
Molecular Weight | 606.7 g/mol |
Molecular Formula | C19H27N4NaO9S4 |
Canonical SMILES | C1C(C(=O)N(C1=O)OC(=O)CCSSCCNC(=O)CCCCC2C3C(CS2)NC(=O)N3)S(=O)(=O)[O-].[Na+] |
Purity | 0.98 |
Application | Protein Biology, Protein Labeling, Protein Labeling and Crosslinking |
Storage | Store at -20°C The product is not stable in solution, please dissolve it immediately before use. |
Shipping | Small Molecules with Blue Ice, Modified Nucleotides with Dry Ice. |
※ It should be noted that our product is only used for research, not for clinical use.