Sulfo-NHS-LC-Biotin(98% )

Sulfo-NHS-LC-Biotin(98% )

Catalog	BR00028474
Description	Sulfo-NHS-LC-biotin (Sulfosuccinimidyl 6-(biotinamido) Hexanoate) is an amine-reactive biotinylation agent. As a water-soluble analog of NHS-LC-biotin, Sulfo-NHS-LC-biotin contains a negatively charged sulfonate group on the NHS ring structure, which creates sufficient polarity within the molecule and allows it to be directly added into aqueous reactions without prior dissolution of organic solvents. Sulfo-NHS-LC-biotin covalently binds to amine groups in proteins and other molecules through its NHS ester forming an amide linkage and releasing N-Hydroxysuccinimide. Sulfo-NHS-LC-biotin has a greater length (22.4 A) between a covalently modified molecule and the bicyclic biotin rings than NHS-biotin (13.5 A), which provides the probes a greater opportunity to reach the binding sites deeply buried inside the surface plane of proteins.
Synonyms	C20H29N4NaO9S2
IUPAC Name	2,5-dioxo-1-[6-[5-(2-oxo-1,3,3a,4,6,6a-hexahydrothieno[3,4-d]imidazol-4-yl)pentanoylamino]hexanoyloxy]pyrrolidine-3-sulfonic acid;sodium
Molecular Weight	The product is not stable in solution, please dissolve it immediately before use.
Molecular Formula	127062-22-0
Canonical SMILES	C1C(C(=O)N(C1=O)OC(=O)CCCCCNC(=O)CCCCC2C3C(CS2)NC(=O)N3)S(=O)(=O)O.[Na]
Purity	0.97
Application	Protein Biology, Protein Labeling, Protein Labeling and Crosslinking
Storage	Store at -20°C
Shipping	Small Molecules with Blue Ice, Modified Nucleotides with Dry Ice.

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