- Home
- Products
- Services
- Inquiry
- Career
- Resources
- About Us
- Contact Us
Catalog | BR00028468 |
CAS | 119616-38-5 |
Structure | ![]() |
Description | Sulfo-NHS-Biotin (N-Hydroxysulfosuccinimidobiotin) is an amine-reactive biotinylation reagent. The most common amine-reactive biotinylation reagents can be divied into two basic types, N-hydroxysuccinimide (NHS) esters and carboxylates. Generally, NHS esters biotinylation reagent contains a reactive NHS ring structure that reacts with an amine on the carbonyl group of a protein or other molecules through nucleophilic attack subsequently forming a stable amide linkage and releasing the NHS group. Due to the insolubility of NHS-biotin in aqueous environments, sulfo-NHS-biotin, a water-soluble analog of NHS-biotin, has been developed by attaching a negatively charged sulfonate group on the NHS ring structure, which can be added directly to aqueous reactions without the need for organic solvent dissolution. |
Synonyms | Sulfo-NHS Biotin |
IUPAC Name | sodium;1-[5-[(3aS,6aR)-2-oxo-1,3,3a,4,6,6a-hexahydrothieno[3,4-d]imidazol-4-yl]pentanoyloxy]-2,5-dioxopyrrolidine-3-sulfonate |
Molecular Weight | 443.4 g/mol |
Molecular Formula | C14H18N3NaO8S2 |
Canonical SMILES | C1C(C(=O)N(C1=O)OC(=O)CCCCC2C3C(CS2)NC(=O)N3)S(=O)(=O)[O-].[Na+] |
Purity | ≥98% |
Appearance | A solid |
Shelf Life | >2 years if stored properly |
Storage | Desiccate at -20°C The product is not stable in solution, please dissolve it immediately before use. |
Drug Formulation | This drug may be formulated in DMSO |
Elemental Analysis | C, 37.92; H, 4.09; N, 9.48; Na, 5.18; O, 28.86; S, 14.46 |
Exact Mass | 443.0433 |
HS Tariff Code | 2934.99.9001 |
Shipping | Small Molecules with Blue Ice, Modified Nucleotides with Dry Ice. |
Stock Solution Storage | 0 - 4 C for short term (days to weeks), or -20 C for long term (months). |
※ It should be noted that our product is only used for research, not for clinical use.