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Sulfo-NHS-Biotin(97% )

Sulfo-NHS-Biotin(97% )

Sulfo-NHS-Biotin(97% )
Catalog BR00028476
CAS 119616-38-5
Structure
Description Sulfo-NHS-Biotin (N-Hydroxysulfosuccinimidobiotin) is an amine-reactive biotinylation reagent. The most common amine-reactive biotinylation reagents can be divied into two basic types, N-hydroxysuccinimide (NHS) esters and carboxylates. Generally, NHS esters biotinylation reagent contains a reactive NHS ring structure that reacts with an amine on the carbonyl group of a protein or other molecules through nucleophilic attack subsequently forming a stable amide linkage and releasing the NHS group. Due to the insolubility of NHS-biotin in aqueous environments, sulfo-NHS-biotin, a water-soluble analog of NHS-biotin, has been developed by attaching a negatively charged sulfonate group on the NHS ring structure, which can be added directly to aqueous reactions without the need for organic solvent dissolution.
Synonyms Sulfo-NHS Biotin
IUPAC Name sodium;1-[5-[(3aS,6aR)-2-oxo-1,3,3a,4,6,6a-hexahydrothieno[3,4-d]imidazol-4-yl]pentanoyloxy]-2,5-dioxopyrrolidine-3-sulfonate
Molecular Weight 443.4 g/mol
Molecular Formula C14H18N3NaO8S2
Canonical SMILES C1C(C(=O)N(C1=O)OC(=O)CCCCC2C3C(CS2)NC(=O)N3)S(=O)(=O)[O-].[Na+]
Purity 0.97
Appearance A solid
Application Protein Biology, Protein Labeling, Protein Labeling and Crosslinking
Storage Desiccate at -20°C
The product is not stable in solution, please dissolve it immediately before use.
Shipping Small Molecules with Blue Ice, Modified Nucleotides with Dry Ice.

※ It should be noted that our product is only used for research, not for clinical use.

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