NHS-SS-Biotin(98% )

NHS-SS-Biotin(98% )

Catalog	BR00028458
CAS	142439-92-7
Structure
Description	NHS-SS-biotin (Succinimidyl-2-(biotinamido)-ethyl-1,3-dithiopropionate) is a long-chain cleavable amine-reactive biotinylation reagent that has a spacer arm of 24.3 A in length due to the existence of a cross-bridge within its chemical structure. The long spacer arm creates an increased length between a covalently modified molecule and the bicyclic biotin rings that greatly enhances the ability of the molecule to bind to avidin or streptavidin probes. The NHS ester group of NHS-SS-biotin reacts with the amine groups of proteins and other molecule forming an amide bond and releasing of sulfo-NHS. NHS-SS-Biotin is a water-insoluble molecule that requires the dissolution of organic solvents prior to be added to aqueous reactions.
Synonyms	NHS-SS-Biotin, NHS SS Biotin
IUPAC Name	2,5-dioxopyrrolidin-1-yl 3-((2-(5-((3aS,4S,6aR)-2-oxohexahydro-1H-thieno[3,4-d]imidazol-4-yl)pentanamido)ethyl)disulfanyl)propanoate
Molecular Weight	504.64 g/mol
Molecular Formula	C19H28N4O6S3
Canonical SMILES	O=C(ON1C(CCC1=O)=O)CCSSCCNC(CCCC[C@@H]2SC[C@]([C@]2([H])N3)([H])NC3=O)=O
InChI	InChI=1S/C19H28N4O6S3/c24-14(4-2-1-3-13-18-12(11-30-13)21-19(28)22-18)20-8-10-32-31-9-7-17(27)29-23-15(25)5-6-16(23)26/h12-13,18H,1-11H2,(H,20,24)(H2,21,22,28)/t12-,13-,18-/m0/s1
InChI Key	LBEDTGQHCFODEH-LXIYXOSZSA-N
Purity	≥98%
Appearance	Solid powder
Shelf Life	>2 years if stored properly
Storage	Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Drug Formulation	This drug may be formulated in DMSO
Elemental Analysis	C, 45.22; H, 5.59; N, 11.10; O, 19.02; S, 19.06
Exact Mass	504.1171
HS Tariff Code	2934.99.9001
Shipping	Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Stock Solution Storage	0 - 4 C for short term (days to weeks), or -20 C for long term (months).

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