NHS-SS-11-Biotin

NHS-SS-11-Biotin

Catalog	BR00028454
CAS	142439-92-7
Structure
Description	NHS-SS-11-biotin  is a long-chain cleavable amine-reactive biotinylation reagent that has a spacer arm of 24.3 A in length due to the existence of a cross-bridge within its chemical structure. The long spacer arm creates an increased length between a covalently modified molecule and the bicyclic biotin rings that greatly enhances the ability of the molecule to bind to avidin or streptavidin probes. The NHS ester group of NHS-SS-11-biotin reacts with the amine groups of proteins and other molecule forming an amide bond and releasing of sulfo-NHS. NHS-SS-11-Biotin is a water-insoluble molecule that requires the dissolution of organic solvents prior to be added to aqueous reactions.
IUPAC Name	2,5-dioxopyrrolidin-1-yl 3-((3-oxo-3-((2-(5-((3aS,4S,6aR)-2-oxohexahydro-1H-thieno[3,4-d]imidazol-4-yl)pentanamido)ethyl)amino)propyl)disulfanyl)propanoate
Molecular Weight	575.72 g/mol
Molecular Formula	C22H33N5O7S3
Canonical SMILES	O=C1N[C@]2([H])[C@]([C@H](CCCCC(NCCNC(CCSSCCC(ON3C(CCC3=O)=O)=O)=O)=O)SC2)([H])N1
Purity	0.98
Appearance	A solid
Storage	Store at -20°C
Shipping	Small Molecules with Blue Ice, Modified Nucleotides with Dry Ice.

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