NHS-LC-Biotin(98% )

NHS-LC-Biotin(98% )

Catalog	BR00028452
CAS	72040-63-2
Description	NHS-LC-biotin (succinimidyl-6-(biotinamindo)hexanoate), also known as NHS-X-biotin is a derivative of D-biotin, a amine-reactive biotinylation agent, that contains a spacer arm off the valeric acid side chain of D-biotin with an NHS ester group at its end. The NHS ester group at the end of NHS-LC-biotin covalently binds to amine groups in proteins and other molecules forming a stable amide linkage and releasing the NHS group. The 6-aminocaproic acid spacer of NHS-LC-biotin greatly increases the length between a covalently modified molecule and the bicyclic biotin rings leading to a better binding potential for avidin or streptavidin probes. NHS-LC-biotin is insoluble in aqueous environments requiring the dissolution of organic solvents prior to the addition to a buffered reaction.
Synonyms	Succinimidyl 6-(biotinamido)hexanoate
IUPAC Name	(2,5-dioxopyrrolidin-1-yl) 6-[5-[(3aS,4S,6aR)-2-oxo-1,3,3a,4,6,6a-hexahydrothieno[3,4-d]imidazol-4-yl]pentanoylamino]hexanoate
Molecular Weight	454.54 g/mol
Molecular Formula	C20H30N4O6S
Canonical SMILES	C1CC(=O)N(C1=O)OC(=O)CCCCCNC(=O)CCCCC2C3C(CS2)NC(=O)N3
Purity	0.98
Application	Protein Biology, Protein Labeling, Protein Labeling and Crosslinking
Storage	Store at -20°C
Shipping	Small Molecules with Blue Ice, Modified Nucleotides with Dry Ice.

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