NHS-Biotin(98% )

NHS-Biotin(98% )

Catalog	BR00028460
CAS	35013-72-0
Structure
Description	NHS-Biotin (C14H18O5N3S) is N-hydroxysuccinimido biotin. It is the shortest of three similar EZ-Link NHS-Biotin Reagents that enable simple and efficient biotinylation of antibodies, proteins and any other primary amine-containing biomolecules in solution. NHS-Biotin offers researchers the possibility of optimizing labeling and detection experiments where steric hindrance of biotin binding is an important factor. Because it is uncharged and contain simple alkyl-chain spacer arms, NHS-Biotin compound is membrane-permeable and useful for intracellular labeling. NHS-Biotin is the most popular type of biotinylation reagent. NHS-activated biotins react efficiently with primary amino groups (-NH2) in alkaline buffers to form stable amide bonds. Proteins (e.g., antibodies) typically have several primary amines that are available as targets for labeling, including the side chain of lysine (K) residues and the N-terminus of each polypeptide.
Synonyms	Biotin N-hydroxysuccinimide ester, Biotin-OSU, Biotin NHS, Biotin SE
IUPAC Name	(2,5-dioxopyrrolidin-1-yl) 5-[(3aS,4S,6aR)-2-oxo-1,3,3a,4,6,6a-hexahydrothieno[3,4-d]imidazol-4-yl]pentanoate
Molecular Weight	341.38 g/mol
Molecular Formula	C14H19N3SO5
Canonical SMILES	C1CC(=O)N(C1=O)OC(=O)CCCCC2C3C(CS2)NC(=O)N3
Purity	0.98
Appearance	A solid
Storage	Desiccate at -20°C
Shipping	Small Molecules with Blue Ice, Modified Nucleotides with Dry Ice.

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