Mal-Cyclohexyl-PEG3-Biotin

Mal-Cyclohexyl-PEG3-Biotin

Catalog	BR00028513
CAS	2639395-45-0
Structure
Description	Mal-Cyclohexyl-PEG3-Biotin is a PEG linker containing a maleimide moiety and a biotin group. Maleimides react specifically with sulfhydryl groups to form a stable thioether linkage when the pH is between 6.5 and 7.5. The biotinylation can react with amine molecules in the presence of activator EDC or HATU. PEG attached to the biotin gives an extended spacer arm that permits the biotin to reach into the binding pocket of the protein. The PEG moiety also increases solubility of Biotin-PEG conjugates considerably. Reagent grade, for research purpose. Please contact us for GMP-grade inquiries.
Synonyms	Mal-Cyclohexyl-PEG3-Biotin
IUPAC Name	4-((2,5-dioxo-2,5-dihydro-1H-pyrrol-1-yl)methyl)-N-(13-oxo-17-((3aS,4S,6aR)-2-oxohexahydro-1H-thieno[3,4-d]imidazol-4-yl)-3,6,9-trioxa-12-azaheptadecyl)cyclohexane-1-carboxamide
Molecular Weight	637.79 g/mol
Molecular Formula	C30H47N5O8S
Canonical SMILES	[H][C@]1(N2)CS[C@@H](CCCCC(NCCOCCOCCOCCNC(C3CCC(CN4C(C=CC4=O)=O)CC3)=O)=O)[C@@]1([H])NC2=O
InChI	InChI=1S/C30H47N5O8S/c36-25(4-2-1-3-24-28-23(20-44-24)33-30(40)34-28)31-11-13-41-15-17-43-18-16-42-14-12-32-29(39)22-7-5-21(6-8-22)19-35-26(37)9-10-27(35)38/h9-10,21-24,28H,1-8,11-20H2,(H,31,36)(H,32,39)(H2,33,34,40)/t21?,22?,23-,24-,28-/m0/s1
InChI Key	YVEORNHVGGJXOZ-UNPLWTFOSA-N
Purity	≥98%
Appearance	To be determined
Shelf Life	>2 years if stored properly
Storage	Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Drug Formulation	To be determined
Elemental Analysis	C, 56.50; H, 7.43; N, 10.98; O, 20.07; S, 5.03
Exact Mass	637.3145
HS Tariff Code	2934.99.9001
Shipping	Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Stock Solution Storage	0 - 4 C for short term (days to weeks), or -20 C for long term (months).

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