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Fumagillin

Fumagillin

Fumagillin
Catalog BR00028553
CAS 23110-15-8
Structure
Description Fumagillin(NSC9168) is an antimicrobial compound first isolated in 1949 from the fungus Aspergillus fumigatu. Fumagillin can inhibits HIV-1 infection through the inhibition of HIV-1 viral protein R (Vpr) activity.
Synonyms NSC9168; NSC 9168; NSC-9168; Fumidil B; Fumagillin, trade name: Fumagilina; Fugillin; Fumidil.
IUPAC Name (2E,4E,6E,8E)-10-(((3R,4S,5S,6R)-5-methoxy-4-((2R)-2-methyl-3-(3-methylbut-2-en-1-yl)oxiran-2-yl)-1-oxaspiro[2.5]octan-6-yl)oxy)-10-oxodeca-2,4,6,8-tetraenoic acid
Molecular Weight 458.55 g/mol
Molecular Formula C26H34O7
Canonical SMILES O=C(O)/C=C/C=C/C=C/C=C/C(O[C@H](CC1)[C@@H](OC)[C@H]([C@@]2(C)OC2C/C=C(C)\C)[C@]31CO3)=O
InChI InChI=1S/C26H34O7/c1-18(2)13-14-20-25(3,33-20)24-23(30-4)19(15-16-26(24)17-31-26)32-22(29)12-10-8-6-5-7-9-11-21(27)28/h5-13,19-20,23-24H,14-17H2,1-4H3,(H,27,28)/b7-5+,8-6+,11-9+,12-10+/t19-,20?,23-,24-,25+,26+/m1/s1
InChI Key NGGMYCMLYOUNGM-IJIYPQOHSA-N
Melting Point 194-195°C
Purity ≥98%
Appearance Solid powder
Shelf Life >2 years if stored properly
Storage Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Drug Formulation This drug may be formulated in DMSO
Elemental Analysis C, 68.10; H, 7.47; O, 24.42
Exact Mass 458.23045
HS Tariff Code 2934.99.9001
Shipping Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Stock Solution Storage 0 - 4 C for short term (days to weeks), or -20 C for long term (months).

※ It should be noted that our product is only used for research, not for clinical use.

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