Biotin-Azide(≥97% )

Biotin-Azide(≥97% )

Catalog	BR00028420
CAS	1006592-62-6
Structure
Description	Biotin azide reacts with the terminal alkynes via a copper-catalyzed click reaction, including biomolecules containing alkyne groups through azide-alkyne cycloaddition. Biotin and biotin derivatives can be readily conjugated to various biomolecules through the well-known click chemistry and subsequently detected with streptavidin, avidin or NeutrAvidin biotin-binding protein. Biotin azide can be used to prepare various biotinylated conjugates via Click Chemistry. Click chemistry contains a class of chemical reactions that use bio-orthogonal or biologically unique moieties to label and detect the molecule in mild and aqueous conditions. This reagent allows labeling of various alkynylated molecules, such as DNA, oligonucleotides, and proteins with biotin. Biotin binding to avidin or streptavidin could be used in downstream affinity applications for the isolation of biotinylated molecules or their binding with streptavidin conjugates [1].
Synonyms	Biotin-Azide
IUPAC Name	N-(6-azidohexyl)-1-(5-((3aS,4S,6aR)-2-oxohexahydro-1H-thieno[3,4-d]imidazol-4-yl)pentanamido)-3,6,9,12-tetraoxapentadecan-15-amide
Molecular Weight	615.79 g/mol
Molecular Formula	C27H49N7O7S
Canonical SMILES	[H][C@@]1(N2)[C@]([C@H](CCCCC(NCCOCCOCCOCCOCCC(NCCCCCCN=[N+]=[N-])=O)=O)SC1)([H])NC2=O
InChI	InChI=1S/C27H49N7O7S/c28-34-31-11-6-2-1-5-10-29-25(36)9-13-38-15-17-40-19-20-41-18-16-39-14-12-30-24(35)8-4-3-7-23-26-22(21-42-23)32-27(37)33-26/h22-23,26H,1-21H2,(H,29,36)(H,30,35)(H2,32,33,37)/t22-,23-,26-/m0/s1
InChI Key	VMDHUTMCBPLPBZ-FXSPECFOSA-N
Purity	≥97%
Solubility	DMSO, DCM, DMF
Appearance	To be determined
Application	Useful for biotinylation of reagents
Storage	Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Item	Biotin-Azide
Shipping	Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

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