Azide-PEG3-Desthiobiotin

Azide-PEG3-Desthiobiotin

Catalog	BR00028489
CAS	1426828-06-9
Structure
Description	Desthiobiotin is a single-ring, sulfur-free analog of biotin that binds to streptavidin with nearly equal specificity but less affinity than biotin (Kd?= 1011?vs. 1015M, respectively). Consequently, desthiobiotinylated proteins can be eluted readily and specifically from streptavidin affinity resin using mild conditions based on competitive displacement with free biotin. For pull-down experiments with biological samples, this soft-release characteristic of desthiobiotin also helps to minimize co-purification of endogenous biotinylated molecules, which remain bound to streptavidin upon elution of the target protein complexes with free biotin. Reagent grade, for research purpose. Please contact us for GMP-grade inquiries.
Synonyms	Azide-PEG3-Desthiobiotin; Desthiobiotin-PEG3-Azide; HY-W096120; BP-22473; CS-0147748; Desthiobiotin-PEG3-Azide
IUPAC Name	N-(2-(2-(2-(2-azidoethoxy)ethoxy)ethoxy)ethyl)-6-((4R,5S)-5-methyl-2-oxoimidazolidin-4-yl)hexanamide
Molecular Weight	414.51 g/mol
Molecular Formula	C18H34N6O5
Canonical SMILES	O=C(NCCOCCOCCOCCN=[N+]=[N-])CCCCC[C@H]([C@H](C)N1)NC1=O
InChI	InChI=1S/C18H34N6O5/c1-15-16(23-18(26)22-15)5-3-2-4-6-17(25)20-7-9-27-11-13-29-14-12-28-10-8-21-24-19/h15-16H,2-14H2,1H3,(H,20,25)(H2,22,23,26)/t15-,16+/m0/s1
InChI Key	JIQVKRRASYKCEL-JKSUJKDBSA-N
Purity	≥98%
Appearance	To be determined
Shelf Life	>2 years if stored properly
Storage	Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Drug Formulation	To be determined
Elemental Analysis	C, 52.16; H, 8.27; N, 20.28; O, 19.30
Exact Mass	414.26
HS Tariff Code	2934.99.9001
Shipping	Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Stock Solution Storage	0 - 4 C for short term (days to weeks), or -20 C for long term (months).

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