Monoclonal Antibody Delivery Based on Avidin-biotin System

Services

Monoclonal antibodies can be used as replacement antibodies to restore, enhance, modify and mimic the immune system's attack on unwanted cells. Antibody drugs made of monoclonal antibodies are currently an effective way to treat many diseases. Monoclonal antibodies are antibodies that mimic your own immune system to have a unique effect on cancer cells. The avidin-biotin hormone enables the delivery of monoclonal antibody payloads to important targets of response. Avidin conjugation helps increase uptake at the target site. Avidin offers greater advantages in the field of drug delivery via monoclonal antibodies. Avidin fusion proteins engineered to be conjugated to monoclonal antibodies have shown excellent target specificity. In order to achieve high specificity for targeting molecules, the avidin-biotin system can be used for the delivery of monoclonal antibodies, which is still in the stage of rapid development.

The Services

Alfa Chemistry insists on providing customers with efficient avidin-biotin-related research, and the services it can provide include but are not limited to:

Expression and purification of fusion protein
In vitro characterization of monoclonal antibodies
Immune reactivity/affinity of monoclonal antibodies
Pharmacokinetics and biodistribution studies
Monoclonal antibody customization service

Our service content and technical support

Alfa Chemistry provides a comprehensive solution that can complete the complete process from monoclonal antibody design, purification and detection. Our scientific researchers can choose the appropriate technology platform according to the target of interest and characteristics of customers. In addition, we also provide professional ELISA, WB, flow cytometry, IHC, cell-based screening, affinity detection and other characterization and screening techniques to ensure the most suitable monoclonal antibodies to meet the needs of research, diagnosis and treatment.

Custom service advantages of monoclonal antibodies

Advanced antibody discovery technology: Professional processing technology and unique technical support
Efficient antibody research and development platform: Rapid immunization, multiple purification methods
Various antigen types: Recombinant protein, natural protein, insect virus, polypeptide
Comprehensive detection platform: ELISA, WB, IHC, IF, FACS and ICC
Customized solutions: According to the needs of customers, we can customize professional experimental solutions and perform efficient purification and screening
Professional design: Experienced experts can support solutions from antigen design to development

Figure 2. Professional design platform, a wide range of sample types, to provide professional customized monoclonal antibody services

Related support

Monoclonal antibody customization
Polyclonal antibody customization

What can we provide?

Our custom monoclonal antibody service can handle all levels of complexity projects, whether it is simple or complex antigens requiring several or more monoclonal antibodies, and can support specific screening services. Our experts will do their best to satisfy customers' needs.

Service process

Understand customer requirements for monoclonal antibodies
According to the preparation needs of customers, a wide range of antigens can be provided
Determine the preparation solution and communicate with technicians in detail
Sign the agreement

Alfa Chemistry provides a comprehensive solution, we will cooperate with customers in an all-round way to complete the complete process from design, purification to detection. If you are interested in our services, please contact us immediately.

Reference:

Akshay. J.; et al. The principles and applications of avidin-based nanoparticles in drug delivery and diagnosis. J Control Release. 2017, 10(245): 27-40.

※ It should be noted that our service is only used for research, not for clinical use.

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