In Vivo Biotinylation Assay

Biotinylation utilizes the strong binding force and high specificity of biotin and nucleophilin/streptavidin system, which has great application potential in purification or detection. Biotinylation is usually used to label protein or nucleic acid-based targets for efficient biotinylation labeling, which can greatly improve the sensitivity of detection. Proteins can be biotinylated by biotin ligases in vivo or in vitro for protein immobilization, detection, purification and visualization. Alfa Chemistry focuses on biotinylation detection in vivo and provides biotinylation services for a variety of biological samples to meet the needs of scientific research. The services we can provide include in vivo platelet biotinylation detection and in vivo protein biotinylation detection. We have perfect biotinylation solutions and strategies, improve the service system, strictly control the service quality, and insist on meeting the needs of customers with high-quality services.

The Services

Alfa Chemistry focuses on efficient biotinylation services, provides a wide range of biotinylation strategies and solutions, and continuously improves the service system. We provide professional chemical biotinylation services, including but not limited to:

• In vivo biotinylated detection of platelets

Platelets, also known as acid cells, are part of the blood. Platelets can be combined with coagulation factors to react blood vessel damage and bleeding sites through agglutination. Platelets do not have a nucleus and are part of the cytoplasm. Blood vessel injury coagulation hemostasis, can be used for coagulation. Thrombocytopenia can lead to bone marrow disease (leukemia or immune system).

• In vivo biotinylation detection proteins

There are a large number of protein-protein interactions in cells, which often act on the whole process of cells. The high-affinity interaction of biotin with avidin or streptavidin has been widely used in biochemistry and molecular biology. In vivo labeling of proteins by covalent attachment of biotin moieties has emerged as a new promising tool for protein detection and purification.

The applications of biotinylation assays

Our team strength and advantages

In Alfa Chemistry, our scientific researchers will participate in the customer's biotinylation service throughout the process and support the detection of various samples. We cooperate with a world-class team to keep pace with the times and insist on innovation to meet the growing needs. We focus on providing professional technology, equipped with advanced equipment, and insist on meeting customer needs. We have a dedicated team that offers a wide range of solutions and strategies to suit a wide range of needs.

Figure 2. We have a first-class team to provide efficient biotinylation services to meet the needs of scientific research

What can we provide?

• Broad range of biotinylation solutions and strategies
• Efficient biological detection service with high universality
• Professional data analysis to support biotinylation test project management
• Optimized service process, saving time, labor and money
• Independently expand the R&D route

Alfa Chemistry has a complete quality assurance system, strictly controls the quality of service, and insists on providing efficient in vivo biotinylation detection services for global customers. If you are interested in our services, please contact us immediately.

References:

1. Ault. A.K.; et al. In vivo biotinylation demonstrates that reticulated platelets are the youngest platelets in circulation. Exp Hematol. 1995, 23(9): 996-1001.
2. Antoine. V.; et al. Use of protein biotinylation in vivo for immunoelectron microscopic localization of a specific protein isoform. J Histochem Cytochem. 2008, 56(10): 911-919.

※ It should be noted that our service is only used for research, not for clinical use.