Carbonyl Biotinylation

Biotinylation refers to the process of attaching biotin to proteins or other biological macromolecules, which can be used for the detection and purification of proteins or antibodies. Biotin is an ideal choice for labeling proteins and biological macromolecules, mainly due to its small molecular weight, strong anti-interference ability and high quality of specific binding. Biotinylation reagents can be used to target specific functional groups such as primary amines, sulfhydryls, carboxyl groups, and carbohydrates. Non-specific biotinylation is also possible, usually by exposure to UV light. Carbonyl groups do not exist in natural materials in nature, but proteins can generate carbonyl groups through oxidation, which can be used for biotinylation labeling. Alfa Chemistry specializes in providing high-quality biotinylation services, constantly innovating and developing, insisting on optimizing service processes, and meeting customer needs with high-quality services.

Proteins containing aldehyde groups or ketones can be converted into carbonyl groups by oxidation, enabling efficient biotinylation. Alfa Chemistry provides a wide range of biotinylation strategies and can provide related carbonyl biotinylation services including but not limited to:

• Efficient carbonyl biotinylation
• Calculation of binding affinity
• Efficient testing of carbonyl biotinylation

Considerations for specific applications and target proteins

• Solubility: The solubility of biotinylation reagents affects the ability to label proteins
• The length of the spacer arm: The binding of biotin and avidin is affected by the length of the spacer arm
• Reversibility: Recovery or purification through reversible biotin-avidin interaction
• Functional group modification: Specific reactive properties enable non-selective or targeted biotinylation

What can we offer？

• Carbonyl-targeted antibody biotinylation for better control of the biomarker process
• Enables efficient biotinylation services to support biomolecules with multiple functional groups
• Provide a wide range of biotinylation solutions and strategies to adhere to customer needs

The advantages of biotinylation services

Alfa Chemistry focuses on advanced biotinylation services, insists on optimizing the detection platform, and meets the needs of customers with cost-effective services. The biotinylation service we can provide has the following advantages:

Professional team strength

Alfa Chemistry provides professional biotinylation solutions and strategies, insists on improving the service system, and optimizes the quality assurance system to meet the needs of customers.

Alfa Chemistry can meet customers' biotinylation services on time, budget and function. Our experienced scientific researchers implement fast biotinylation project response services, providing services with competitive prices to meet customer needs. If you are interested in our services, please contact us immediately.

※ It should be noted that our service is only used for research, not for clinical use.